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A high-pressure situation

delete2023-07-01
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PRE
AI
M
Matthew J. Miller
J
John Hicks
R
Rod Foroozan *
M
Michael C. Brodsky
DOI:10.1016/j.survophthal.2022.08.001delete
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Abstract

Abstract

En 中文
An 8-year-old boy presented with acute visual loss in the right eye and nausea, vomiting, and diplopia. Imaging revealed a right orbital apex mass. Biopsy showed Langerhans cell histiocytosis (LCH), and the patient was diagnosed with isolated orbital LCH causing an or-bital apex syndrome. A 12-month cytarabine chemotherapy course was begun, during which the patient developed bilateral optic disc edema. He was diagnosed with cytarabine-induced intracranial hypertension, which was successfully treated with acetazolamide. The cytara-bine course was completed with complete resolution of the LCH lesion. The ophthalmologic relevance of this rare disorder is discussed.& COPY; 2022 Elsevier Inc. All rights reserved.
Keywords:
Langerhans cell histiocytosis (LCH)
Orbital apex syndrome
Cytarabine
Intracranial hypertension

Journal

Survey of Ophthalmology cover
Survey of Ophthalmology
IF:
5.9
Papers:
2.4K
Citations:
7.8K

Organization

B
Baylor College of Medicine
Scholars:
4.1W
Papers: 3.0W
Citations: 4.2W
B
baylor college medical hospital
Scholars:
6.5K
Papers: 4.7K
Citations: 7