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A hybrid deconvolution algorithm in three-dimensional fluorescence microscopy
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DOI：10.1016/j.rineng.2026.112095.png)
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Abstract
En 中文
• A hybrid deconvolution method for 3D fluorescence microscopy is proposed. • Effectively subtracts out-of-focus background prior to RL refinement. • The method minimizes defocus halos and improves structural fidelity. • Drives scattering background to near-zero in thick-tissue neuronal imaging.
Keywords:
Fluorescence microscopy
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Richardson–Lucy
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