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A literature review of the pharmacokinetic profiles of 20 commonly prescribed antihypertensive medications for use in chemical adherence testing
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DOI：10.1097/HJH.0000000000004333.png)
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Abstract
En 中文
Nonadherence to antihypertensive medications is a major concern, with significant implications for healthcare systems and patient outcomes. Chemical adherence testing (CAT) is a recommended method to assess nonadherence objectively by detecting drugs or their metabolites in blood or urine samples. Interpretation of CAT results require relevant pharmacokinetic parameters. However, pharmacokinetic data in established sources are not graded for quality and not compiled into a single resource.
Keywords:
antihypertensive medications
chemical adherence testing
half-life
hypertension
minimum concentration
nonadherence
peak concentration
pharmacokinetics
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