arrow
Return

A meshless multiscale method for simulating hemodynamics

delete2023-05-01
delete3
PRE
AI
K
Kyle W. Beggs *
E
Eduardo Divo
A
Alain J. Kassab
DOI:10.1016/j.enganabound.2023.01.032delete
deleteOriginal
deleteOriginal request for help
deleteShare
deleteSave
Abstract

Abstract

En 中文
Simulating hemodynamic quantities such as pressure and velocity are of great interest to clinicians to aid in surgical planning. To accurately simulate modifications to a region of vasculature, the entire system must be modeled. To facilitate this, a localized Radial-Basis Function (RBF) collocation Meshless flow solver is developed and tightly coupled to a 0D Lumped-Parameter Model (LPM) for solution of the peripheral circulation. The Meshless solver uses localized RBF collocations at data points that are automatically generated according to the geometry. The incompressible flow equations are updated by an explicit time-marching scheme based on a pressure-velocity correction algorithm. The inlets and outlets of the domain are tightly coupled with the LPM which contains elements that draw from a fluid-electrical analogy such as resistors, capacitors, and inductors that represent the viscous resistance, vessel compliance, and flow inertia, respectively. The localized RBF Meshless approach is well-suited for modeling complicated non-Newtonian hemodynamics due to ease of spatial dis-cretization, ease of addition of multi-physics interactions such as fluid-structure interaction of the vessel wall, and ease of parallelization for fast computations. This work introduces the tight coupling of Meshless methods and LPMs for fast and accurate hemodynamic simulations.
Keywords:
Meshless
Hemodynamics
Radial Basis Functions
RBF-FD
Multiscale modeling

Journal

Engineering Analysis with Boundary Elements cover
Engineering Analysis with Boundary Elements
IF:
4.1
Papers:
5.9K
Citations:
9.4K

Organization

State University System of Florida cover
State University System of Florida
Scholars:
12.8W
Papers: 10.9W
Citations: 130
U
University of Central Florida
Scholars:
8.7K
Papers: 6.8K
Citations: 1.4W
Cited Papers

Cited Papers

Residual Structure in Islet Amyloid Polypeptide Mediates Its Interactions with Soluble Insulin
err2009-01-15
err0
PREAI
errLei Wei; Ping Jiang; Yin Hoe Yau; Heike Summer; Susana Geifman Shochat; Yuguang Mu; Konstantin Pervushin
errShare
errSave
Elder Abuse Screening and Intervention
err1986-05-01
err0
PREAI
errTerry Fulmer; Terrie Wetle
errShare
errSave
errShare
errSave
Photophysical Properties of ZnS Nanoclusters with Spatially Localized Mn2+
err1996-03-14
err0
PREAI
errKelly Sooklal; Brian S. Cullum; S. Michael Angel; Catherine J. Murphy
errShare
errSave
errShare
errSave
researcher View more