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A Miniaturized Ingestible Capsule With Integrated ASIC for Energy-Efficient Sensing in the Gastrointestinal Tract

delete2026-01-01
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PRE
AI
R
Ramzy Rammouz *
V
Vasileios Adamopoulos
M
Miller, Ivan D. Castro
W
Wim Sijbers
R
Ria Sijabat
D
Dimitrios Firfilionis
Q
Qiuyang Lin
B
Benjamin Calmé
T
Tom Torfs
DOI：10.1109/OJCAS.2026.3664175delete
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Abstract

Abstract

En 中文
Recent efforts have focused on wireless ingestible sensing capsules, but challenges remain in miniaturization, sensor integration, and energy efficiency. This paper presents GISMO-A, an ingestible capsule integrating a custom-designed application-specific integrated circuit (ASIC) for low-power biochemical sensing. The ASIC enables pH and oxidation-reduction potential (ORP) measurements at an average power consumption of 172 mu W, representing a 70% reduction compared to the previously published GISMO capsule. GISMO-A supports a 6-second measurement interval, resulting in a threefold increase in data density relative to GISMO. Validated through in-vitro and in-vivo experiments, GISMO-A represents a significant advancement in the design of energy-efficient, miniaturized GI Tract sensing systems.
Keywords:
Application specific integrated circuit
biochemical sensing
low-power
gastrointestinal tract
ingestible capsule
miniaturized
temporal resolution

Journal

I
IEEE Open Journal of Circuits and Systems
IF:
2.4
Papers:
4.5K
Citations:
387

Organization

I
interuniversity microelectronics centre
Scholars:
6.2K
Papers: 3.9K
Citations: 0
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