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A multi-scale modeling approach for infectious disease: Integrating within-host dynamics to network-based transmission
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DOI：10.1016/j.apm.2026.117220.png)
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Abstract
En 中文
• A multiscale model links viral dynamics to multilayer contact networks. • Viral-load data generate pathogen-specific infectiousness profiles. • Infectiousness timing alters epidemic peaks and epidemic duration. • Contact layers shape setting-specific transmission across pathogens. • Intervention effects depend on temporal infectiousness profiles.
Keywords:
Multi-scale modeling
Within-host dynamics
Contact network
Agent-based simulation
Epidemic control
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