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A nanozyme-engineered implant surface for sequential photodynamic antibacterial and cytoprotective functions

delete2026-04-30
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PRE
AI
S
Shuai Yan
N
Nan Hu
B
Ben Wu
M
Minggang Yang
J
Jie Wei *
G
Guocheng Wang *
H
Hualin Ma *
DOI:10.1016/j.colsurfb.2026.115757delete
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Abstract

Abstract

En 中文
• Stepwise hydrothermal fabrication of hierarchical TiO2/CoMn2O4 on Ti alloy. • An “attack-defense” strategy resolves the antibacterial-osteogenesis conflict. • NIR-responsive TiO2 metastructure functions as the “attack” layer for on-demand sterilization. • In-situ CoMn2O4 nanozyme serves as the “defense” layer, scavenging ROS to protect cells. • The surface achieves > 90% antibacterial rate and significantly enhances osteogenesis.
Keywords:
TiO2/CoMn2O4
nanozyme
antibacterial
osteogenesis
photodynamic

Journal

C
Colloids and Surfaces B: Biointerfaces
IF:
5.6
Papers:
1.4W
Citations:
4.2W

Organization

E
east china university of science and technology
Scholars:
7.3K
Papers: 2.4K
Citations: 3
S
southern university of science and technology
Scholars:
3.7K
Papers: 1.4K
Citations: 0
C
chinese academy of sciences
Scholars:
54.9W
Papers: 44.5W
Citations: 703
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