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A novel macrolide, EP395, with reduced antibacterial activity and an enhancing effect on respiratory epithelial barrier
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DOI：10.1016/j.pupt.2025.102363.png)
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Abstract
En 中文
- EP395 is a novel macrolide with negligible antimicrobial activity - In vitro EP395 dose-dependently increases bronchial epithelial barrier integrity - EP395 has a similar beneficial gene expression profile to AZM in bronchial epithelial cells
Keywords:
Macrolides
Epithelial barrier
Gene expression
COPD
Azithromycin
EP395
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