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A novel surrogate-based optimisation framework for pharmaceutical process systems
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DOI：10.1016/j.ijpharm.2025.125861.png)
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Abstract
En 中文
• Unified framework for surrogate-based optimisation. • Supports both single- and multi-objective optimisation versions. • Case study uses dynamic system model of an API manufacturing process. • Pareto fronts reveal trade-offs between competing objectives. • Impact of variables shown via sensitivity analysis and optimisation results.
Keywords:
Process Optimisation
Multi-objective
Surrogate model
Pharmaceutical industry
Sustainability
Journal
IF:
5.2
Papers:
2.2W
Citations:
6.7W
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