.png){kind=icon}
.png){kind=icon}
Return
A polyadenylation enzyme rewires metabolism to fuel AML
.png){kind=icon}
PRE
AI
A
D
DOI：10.1038/s43018-026-01180-9.png)
.png){kind=icon}
Original request for help.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
mRNA polyadenylation is a tightly controlled process, but its role in cancer remains poorly understood. A study now shows that the RNA-modifying enzyme poly(A) polymerase α (PAPOLA) is crucial for acute myeloid leukemia generation and progression via an axis that can be effectively targeted therapeutically, offering new hope for patients.