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A rationally designed intramolecular aptamer switch for rapidly sensing oxytetracycline
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DOI：10.1016/j.ab.2026.116107.png)
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Abstract
En 中文
• A simple intramolecular aptamer switch for rapid detection of oxytetracycline (OTC) within 3 minutes. • This switchable aptamer, which undergo a remarkable conformational change upon binding to OTC, can translate binding events into fluorescence for measurement. • Benefitting from the high efficient intramolecular reaction, this aptamer switch has a low background and a large signal variation, availing sensitivity.
Keywords:
aptamer switch
oxytetracycline
fluorescence detection
conformational change
rapid sensing