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A self-reference PRF-shift MR thermometry method utilizing the phase gradient
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DOI：10.1088/0031-9155/56/24/N02.png)
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Abstract
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In magnetic resonance (MR) imaging, the most widely used and accurate method for measuring temperature is based on the shift in proton resonance frequency (PRF). However, inter-scan motion and bulk magnetic field shifts can lead to inaccurate temperature measurements in the PRF-shift MR thermometry method. The self-reference PRF-shift MR thermometry method was introduced to overcome such problems by deriving a reference image from the heated or treated image, and approximates the reference phase map with low-order polynomial functions. In this note, a new approach is presented to calculate the baseline phase map in self-reference PRF-shift MR thermometry. The proposed method utilizes the phase gradient to remove the phase unwrapping step inherent to other self-reference PRF-shift MR thermometry methods. The performance of the proposed method was evaluated using numerical simulations with temperature distributions following a two-dimensional Gaussian function as well as phantom and in vivo experimental data sets. The results from both the numerical simulations and experimental data show that the proposed method is a promising technique for measuring temperature.
Keywords:
MAGNETIC-RESONANCE THERMOMETRY
FOCUSED ULTRASOUND SURGERY
PROTON CHEMICAL-SHIFT
FREQUENCY-SHIFT
MAPPING METHOD
TISSUE
MOTION
ORGANS
WATER
OPTIMIZATION
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