.png){kind=icon}
.png){kind=icon}
Return
A self-sustaining repair circuit drives the progression of pulmonary fibrosis
.png){kind=icon}
PRE
AI
D
T
H
T
DOI：10.1016/j.trsl.2026.07.015.png)
.png){kind=icon}
Original request for help.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
Pulmonary fibrosis is a progressive and often fatal lung disorder whose clinical behavior is not fully explained by conventional injury-driven models. Fibrosis frequently progresses after the initiating insult has resolved, anti-inflammatory therapies have shown limited benefit in idiopathic pulmonary fibrosis, and current antifibrotic drugs slow but rarely reverse disease progression. Moreover, diverse conditions including idiopathic pulmonary fibrosis, post-ARDS or post-infectious fibrosis, radiation-induced injury, drug toxicity, and bronchopulmonary dysplasia arise from distinct causes yet may converge toward shared features of persistent fibrotic remodeling.
Journal
IF:
5.9
Papers:
2.0K
Citations:
7.1K
Organization
Cited Papers