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A solid-state intraoperative beta probe system
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DOI：10.1109/23.870863.png)
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Abstract
En 中文
Successful beta-sensitive intraoperative probes must be capable of detecting relatively small amounts of beta-emitting radionuclides in an environment where a significant photon background exists. The probe system described in this investigation utilized a new photon correction scheme consisting of a stack of two ion-implanted-silicon detectors (IISD's) mounted in a compact unit. The rear detector operated as a photon monitor, whose data mas used to correct for photon contamination present in the front detector's readings. The completely battery-powered system incorporated a computer-controlled data acquisition and processing system. Positron and photon detection sensitivities were measured using Fluorine-18, The probe was found to have a positron detection sensitivity of 7.21 +/- 0.11 cps/nCi and a 0.0004 +/- 0.0389 cps/nCi photon detection sensitivity. In a simulated search for tumor remnants following a tumor resection using a phantom presenting a realistic annihilation photon background, the intraoperative probe was capable of definitively identifying 12-mm- and 6-mm-diameter, 1-mm-thick disks of simulated tumor. Localization of a 3-mm-diameter disk was also demonstrated. These excellent results indicate that this system may be a useful aid for radionuclide-guided cancer surgeries.
Keywords:
beta probes
radiation detectors
radionuclide-guided surgery
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