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A succinylation-based classifier predicts chemotherapy response in prostate cancer and reveals KAT2A as a therapeutic target
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DOI：10.1002/ctm2.70737.png)
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Abstract
En 中文
Chemotherapy resistance remains a critical hurdle in advanced prostate cancer (PCa). Succinylation, an essential post-translational modification linking cellular metabolism with epigenetic regulation, has been implicated in tumour progression; however, its contribution to PCa chemoresistance remains poorly defined.
Keywords:
chemoresistance
KAT2A
prostate cancer
succinylation
tumour microenvironment
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