A sui generis whipping-instability-based self-sequencing multi-monodisperse 2D spray from an anisotropic microfluidic liquid jet device

Sankar Raju Narayanasamy

doi:10.1016/j.xcrp.2022.101221

A sui generis whipping-instability-based self-sequencing multi-monodisperse 2D spray from an anisotropic microfluidic liquid jet device

2023-01-01

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Sankar Raju Narayanasamy

R

Ramakrishna Vasireddi

DOI：10.1016/j.xcrp.2022.101221

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Well-defined aerosols pave the way for versatile basic and applied research. Here, we demonstrate a unique whipping instability that generates from a high-aspect-ratio microfluidic device resulting in a unique steady-state gas-focused whipping jet (WJ) without any need for electrification. This WJ device emanates a multi-monodis-perse whipping spray jet with a two-dimensional (2D) profile. We demonstrate this phenomenon based on various fluidic parameters theoretically and experimentally. The 2D WJ's unique behavior is derived using analytical fluid dynamics to explain jet diameter, whipping regime, and spreading angle. The phenomenon is further characterized experimentally by measuring the angle with respect to the flow rate, the distances between droplets, the droplet shapes, and the reproducibility of these parameters. We also explain the precise fabrication of such inexpensive devices. Lastly, we highlight these devices' potential use as sample environments in versatile applications ranging from cryoelectron microscopy over mass spectrometry to drug formulation and structural studies at X-ray free-electron lasers.

A sui generis whipping-instability-based self-sequencing multi-monodisperse 2D spray from an anisotropic microfluidic liquid jet device

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