1
Return

Abbreviated non-contrast magnetic resonance enterography for Crohn’s disease: a reliability study

delete2026-06-05
delete0
delete
OA
AI
V
Valentina Caliendo
V
Vittorio Patanè *
L
Luca Marinelli
A
Anna Russo
M
Maria Chiara Brunese
F
Francesco Selvaggi
A
Antonietta Gerarda Gravina
S
Salvatore Cappabianca
A
Alfonso Reginelli
DOI:10.1007/s11547-026-02227-8delete
deleteOriginal
deleteShare
deleteSave
View PDF
Abstract

Abstract

En 中文
To evaluate the diagnostic reliability and time efficiency of an abbreviated non-contrast magnetic resonance enterography (MRE) protocol for assessing Crohn’s disease activity. This retrospective study included 312 patients who underwent MRE between March 2024 and November 2025. An abbreviated dataset was derived from each full examination by masking sequences not included in the abbreviated protocol, such as all contrast-enhanced acquisitions. Two radiologists independently reviewed the abbreviated and full datasets in separate sessions, fully blinded to clinical information and the alternative dataset. The interpretation of the full MRE dataset served as the reference standard. Outcomes included agreement (Cohen’s kappa), sensitivity and specificity for active disease, image quality ratings (4-point scale), and estimated acquisition time. Agreement for overall disease activity was substantial (κ = 0.83), with sensitivity of 92.3% and specificity of 94.6% for detecting active disease. Agreement was strong for bowel wall thickening (κ = 0.85), mural edema (κ = 0.81), and the comb sign (κ = 0.79). Estimated acquisition time was 44% shorter for the abbreviated protocol (21.6 vs. 38.4 min), while diagnostic image quality was preserved (mean 3.5 ± 0.6). An abbreviated non-contrast MRE protocol provides reliable assessment of Crohn’s disease activity with markedly reduced scan time and maintained image quality, supporting its use in selected follow-up scenarios.
Keywords:
Magnetic resonance enterography
Crohn’s disease
Inflammatory bowel disease
Non-contrast magnetic resonance imaging
Abbreviated protocol
Diagnostic accuracy
AI Summary

AI Summary

Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.

Journal

La radiologia medica cover
La radiologia medica
IF:
4.8
Papers:
206
Citations:
0

Organization

E
Error
Scholars:
1.9K
Papers: 731
Citations: 0
D
department of advanced medical and surgical sciences
Scholars:
108
Papers: 42
Citations: 0
P
Precision Medicine
Scholars:
34
Papers: 14
Citations: 0
Cited Papers

Cited Papers

Citing Papers

Citing Papers