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Abnormal glucose metabolism and muscle mass decline by bisphenol A or bisphenol S in skeletal muscle of male mice:inhibition of mitophagy by downregulation of the ERα/AMPK/ULK1 pathway

delete2026-08-09
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PRE
AI
M
Mingyue Zhao
J
Jiarong Song
王家启 cover
王家启 (Jiaqi Wang)
Y
Yishan Chen
Y
Yue Zhao
Y
Youdan Dong
L
Lingling Zhai
L
Lihong Jia *
DOI:10.1016/j.envres.2026.125392delete
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Abstract

Abstract

En 中文
• BPA or BPS exposure caused abnormal glucose metabolism and muscle mass decline. • BPA or BPS exposure inhibited mitophagy by downregulating the ERα/AMPK/ULK1 pathway. • Abnormal mitophagy disrupted insulin signaling and apoptosis-differentiation balance. • This study links BPA or BPS exposure to the comorbidity of T2DM and sarcopenia.

Journal

Environmental Research cover
Environmental Research
IF:
7.7
Papers:
2.0W
Citations:
9.0W

Organization

C
china medical university
Scholars:
3.9K
Papers: 1.3K
Citations: 0
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