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Accuracy of the FIB-4 and LiverRisk score for use in primary risk assessment for liver fibrosis, and variation by age

delete2026-06-11
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M
Mary E. Rinella
M
Michael R. Charlton
Y
Yestle Kim
S
Suneil Hosmane
J
Jonathan J. Woolley
T
Tom O’Connell *
DOI:10.1016/j.dld.2026.04.011delete
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Abstract

Abstract

En 中文
Primary risk assessment for liver fibrosis involves the Fibrosis-4 (FIB-4) index, a non-invasive test (NIT) reported to have suboptimal accuracy with lower prevalence of fibrosis, particularly at younger ages. The LiverRisk score (LRS) is a NIT developed for general-population prediction of liver fibrosis and liver-related outcomes.
Keywords:
Classification
Accuracy
Risk assessment
Fib-4
LiverRisk score
LRS
Liver fibrosis
MASLD
NHANES
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Digestive and Liver Disease cover
Digestive and Liver Disease
IF:
3.8
Papers:
1.2W
Citations:
8.7K

Organization

M
medicus economics
Scholars:
10
Papers: 7
Citations: 0
M
madrigal pharmaceuticals, inc.
Scholars:
7
Papers: 3
Citations: 0
P
pritzker school of medicine
Scholars:
8
Papers: 7
Citations: 0
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