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Acoustic Atomization-Induced Pumping Based on a Vibrating Sharp-Tip Capillary
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DOI：10.3390/mi14061212.png)
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Abstract
En 中文
Pumping is an essential component in many microfluidic applications. Developing simple, small-footprint, and flexible pumping methods is of great importance to achieve truly lab-on-a-chip systems. Here, we report a novel acoustic pump based on the atomization effect induced by a vibrating sharp-tip capillary. As the liquid is atomized by the vibrating capillary, negative pressure is generated to drive the movement of fluid without the need to fabricate special microstructures or use special channel materials. We studied the influence of the frequency, input power, internal diameter (ID) of the capillary tip, and liquid viscosity on the pumping flow rate. By adjusting the ID of the capillary from 30 & mu;m to 80 & mu;m and the power input from 1 V-pp to 5 V-pp, a flow rate range of 3 to 520 & mu;L/min can be achieved. We also demonstrated the simultaneous operation of two pumps to generate parallel flow with a tunable flow rate ratio. Finally, the capability of performing complex pumping sequences was demonstrated by performing a bead-based ELISA in a 3D-printed microdevice.
Keywords:
acoustofluidic pump
atomization-based pumping
vibrating sharp-tip
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