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Active surveillance of cervical intraepithelial neoplasia and adverse pregnancy outcomes: A register-based cohort study
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DOI：10.1111/aogs.70304.png)
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Abstract
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Previous studies have suggested that human papillomavirus (HPV) and HPV-related disease may be associated with increased risk of adverse pregnancy outcomes, e.g., hypertensive disorders of pregnancy, small for gestational age (SGA), and gestational diabetes mellitus (GDM). As active surveillance for cervical intraepithelial neoplasia grade 2 (CIN2) leaves the lesion and underlying infection untreated, we aimed to investigate whether the risk of adverse pregnancy outcomes differs between women who undergo active surveillance for CIN2 compared to women having an immediate large loop excision of the transformation zone (LLETZ).
Keywords:
active surveillance
adverse pregnancy outcomes
cervical intraepithelial neoplasia grade 2
eclampsia
gestational diabetes mellitus
gestational hypertension
LLETZ
preeclampsia
small for gestational age
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