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Adaptive Framework for Data-Driven Probabilistic Design Space Identification
DOI:10.1016/j.ces.2026.124255.png)
Abstract
En 中文
• Design space identification for systems without reliable mechanistic models • Feasibility-informed sampling guides efficient exploration of feasible regions • Modified Delaunay triangulation method enables adaptive, geometry-driven sampling • Deterministic strategy yields consistent and reproducible design space estimates • Reduces experimentation and avoids variability seen in batch Bayesian optimization
Keywords:
Quality by Design
Design Space Identification
Adaptive Sampling
Design of Experiments
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4.3
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2.3W
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5.5W
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Cited Papers
An Optimization-Based Framework to Define the Probabilistic Design Space of Pharmaceutical Processes with Model Uncertainty
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