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Addressing the Lp(a) hypothesis: will lowering Lp(a) decrease the risk of cardiovascular events?
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DOI：10.1038/s41569-026-01278-8.png)
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Abstract
En 中文
Elevated plasma concentrations of lipoprotein(a) (Lp(a)) are an important risk factor for several cardiovascular diseases. However, to date, elevated Lp(a) levels have not been directly targeted by clinicians because Lp(a) levels are almost entirely genetically determined and are comparatively resistant to standard lipid-lowering therapies. This unmet medical need might soon be addressed with the advent of potent Lp(a)-lowering therapies.
Keywords:
Lipoproteins
Risk factors
Medicine/Public Health
general
Cardiology
Cardiac Imaging
Cardiac Surgery
Journal
IF:
44.2
Papers:
293
Citations:
2.2W