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Advanced Molecular and Biosensing Technologies for HPV-positive head and neck squamous cell carcinoma
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DOI:10.1016/j.trac.2026.119055.png)
Abstract
En 中文
• Liquid biopsies detect ctHPV DNA and microRNAs for non-invasive tumor surveillance. • ddPCR assays detect cancer recurrence an average of 207 days before standard imaging. • Nanomaterial-modified biosensors lower viral detection limits to femtomolar levels. • Deep learning models classify HPV status directly from cost-effective H&E slides. • HPV-positive HNSCC cases are increasing in younger, non-smoking populations driven by E6/E7 drivers.
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