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Advances in magnesium alloy scaffolds as next-generation anticancer platforms
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DOI：10.1016/j.jma.2026.102160.png)
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Abstract
En 中文
• Mechanistic framework linking Mg2+, H2, and OH− to tumor-selective cytotoxicity. • Immunomodulatory effects of Mg degradation in reshaping the tumor microenvironment. • Evaluation of Mg-based stents, microspheres, and 3D-printed scaffolds for cancer therapy. • Key translation barriers: degradation control, biosafety risks, regulatory rules, and imaging compatibility. • Smart Mg platforms with pH-responsive, photothermal, and drug-release functionalities.
Keywords:
Anticancer mechanism
Biomedical magnesium alloy
Future directions
Therapeutic application
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