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Advances in single-cell and spatial multi-omics for plant development and stress responses
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DOI：10.1016/j.pld.2026.07.015.png)
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Abstract
En 中文
• Recent advances in scRNA-seq, snATAC-seq, spatial transcriptomics, and spatial metabolomics are systematically synthesized with a focus on plant systems. • Emerging evidence highlights cell-type-specific and spatially organized mechanisms underlying plant responses to abiotic and biotic stresses. • Key technical bottlenecks are critically evaluated, including sample preparation bias, resolution–throughput trade-offs, and cross-modal data integration challenges. • Future perspectives emphasize AI-driven integration, plant cell atlas construction, and applications in crop improvement and synthetic biology.
Keywords:
Single-cell RNA sequencing
Single-nucleus ATAC sequencing
Spatial transcriptomics
Spatial metabolomics
Plant development
Biotic stress
Abiotic stress
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