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Advancing Lignocellulosic Conversion though Biosensor-enabled metabolic engineering

delete2025-08-01
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OA
AI
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Qi Gan
J
Jianli Zhang
X
Xinyu Gong
Y
Yusong Zou
Y
Yajun Yan
DOI:10.1039/D5GC03618Fdelete
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Abstract

Abstract

En 中文
Lignocellulosic biomass holds great potential to produce a wide range of chemicals; including biofuels; biomaterials; and bioactive compounds. Effective utilization of these biomass feedstocks can significantly benefit human well-being while helping to mitigate climate change and reduce the environmental damage associated with fossil fuel use. Microbial synthesis plays a key role in converting biomass into valuable products. However; further optimization of these metabolic pathways is required to improve productivity. The design and optimization of these pathways remain major bottlenecks due to the complexity of biological systems and our limited understanding of them. Biosensors hold significant potential in advancing microbial metabolic engineering and enhancing substrate-to-product bioconversion. In this review; we discuss the major microbial conversion pathways for lignocellulosic biomass; the development and optimization of biosensors; and their applications in efficient biocatalytic processes for lignocellulosic conversion.
Keywords:
lignocellulosic biomass
microbial synthesis
metabolic engineering
biosensors
bioconversion

Journal

Green Chemistry cover
Green Chemistry
IF:
9.2
Papers:
1.3W
Citations:
7.6W

Organization

No organization information available
Cited Papers

Cited Papers

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Lignocellulosic Biomass Valorization for Bioethanol Production: a Circular Bioeconomy Approach
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errDevi, Arti; Bajar, Somvir; Kour, Havleen; Kothari, Richa; Pant, Deepak; Singh, Anita
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A p-Coumaroyl-CoA Biosensor for Dynamic Regulation of Naringenin Biosynthesis in Saccharomyces cerevisiae
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errLiu, Dany; Sica, Maria Sole; Mao, Jiwei; Chao, Lucy Fang-, I; Siewers, Verena
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Recent Biotechnology Advances in Bio-Conversion of Lignin to Lipids by Bacterial Cultures
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errWang, Huan; Peng, Xiaodong; Li, Hu; Giannis, Apostolos; He, Chao
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Synthetic Evolution of Metabolic Productivity Using Biosensors
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errWilliams, Thomas C.; Pretorius, Isak S.; Paulsen, Ian T.
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Valorization of industrial lignin to value-added chemicals by chemical depolymerization and biological conversion
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errNguyen, Linh Thanh; Phan, Dieu-Phuong; Sarwar, Arslan; Tran, My Ha; Lee, Ok Kyung; Lee, Eun Yeol
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Construction of a fluorescent biosensor family
err2009-04-13
err0
errOAAI
errRobert M. De Lorimier; J. Jeff Smith; Mary A. Dwyer; Loren L. Looger; Kevin M. Sali; Chad D. Paavola; Shahir S. Rizk; Shamil Sadigov; David W. Conrad; Leslie Loew; Homme W. Hellinga
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From lignin to valuable products-strategies, challenges, and prospects
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err607
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errWang, Hongliang; Pu, Yunqiao; Ragauskas, Arthur; Yang, Bin
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