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Adversarial batch representation augmentation for batch correction in high-content cellular screening

delete2026-03-21
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OA
AI
L
Lei Tong
X
Xujing Yao
A
Adam Corrigan
L
Long Chen
N
Navin Rathna Kumar
K
Kerry Hallbrook
J
Jonathan Orme
Y
Yinhai Wang *
H
Huiyu Zhou *
DOI:10.1016/j.knosys.2026.115829delete
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Abstract

Abstract

En 中文
• Proposes an Adversarial Batch Representation Augmentation for batch correction. • Models uncertainty of biological batch effects in representation learning. • Uses adversarial learning to identify challenges in the objective function. • Presents a synergistic optimization process for stable training. • Comprehensive experiments validate the effectiveness of the proposed method.
Keywords:
Batch effect
Domain generalization
Cell painting images
siRNA perturbation classification
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K
Knowledge-Based Systems
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7.6
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imperial college london
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nanjing tech university
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university of leicester
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astrazeneca
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