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Aging reprograms the rhythmic transcriptome in the retina

delete2025-06-29
delete0
PRE
AI
Z
Zhijie Wang
L
Lifeng Chen
L
Li Lin
M
Mengai Wu
B
Bin Zheng *
Y
Yuanyuan Fan *
DOI：10.1016/j.exer.2025.110504delete
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Abstract

Abstract

En 中文
• Number of rhythmic genes is significantly reduced in aged mouse retina. • Antigen processing and presentation genes show rhythmic expression pattern in the aging retina. • Genes involved in RNA degradation and proteasome pathways lost their diurnal rhythm with retina aging.
Keywords:
rhythmic genes
antigen processing
RNA degradation
proteasome pathways
aging retina

Journal

Experimental Eye Research cover
Experimental Eye Research
IF:
2.7
Papers:
7.6K
Citations:
1.6W

Organization

W
Wenzhou Medical University
Scholars:
3.3W
Papers: 1.6W
Citations: 3.0W