.png){kind=icon}
.png){kind=icon}
Return
Agmatine diminishes pro-inflammatory response by modulating IL-1β and NF-κB expression in the prefrontal cortex and reverses behavioral impairments following chronic social isolation in rats
.png){kind=icon}
PRE
AI
H
A
G
F
DOI：10.1016/j.pbb.2026.174178.png)
.png){kind=icon}
Original request for help.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
• Chronic social isolation (SI) induces significant behavioral deficits in rats. • SI elevates IL-1β and NF-κB mRNA levels in the prefrontal cortex (PFC). • Agmatine (AGM) treatment effectively reverses SI-induced behavioral deficits. • Agmatine attenuates the SI-induced elevation of IL-1β and NF-κB in the PFC.
Keywords:
Agmatine
Chronic social isolation
IL-1β
NF-κB
Prefrontal cortex
Journal
IF:
2.5
Papers:
7.6K
Citations:
9.9K
Organization
Cited Papers