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An online GPCR structure analysis platform
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DOI：10.1038/s41594-021-00675-6.png)
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Abstract
En 中文
We present an online, interactive platform for comparative analysis of all available G-protein coupled receptor (GPCR) structures while correlating to functional data. The comprehensive platform encompasses structure similarity, secondary structure, protein backbone packing and movement, residue-residue contact networks, amino acid properties and prospective design of experimental mutagenesis studies. This lets any researcher tap the potential of sophisticated structural analyses enabling a plethora of basic and applied receptor research studies. An online and interactive G-protein coupled receptor (GPCR) structure analysis platform allows any researcher to analyze and visualize a plethora of structure-function relationships across the scales of atomic interactions to protein backbone rearrangements.
Keywords:
PROTEIN
DISCOVERY
Journal
N
IF:
10.1
Papers:
4.8K
Citations:
2.8W