.png){kind=icon}
.png){kind=icon}
Return
Antigen Presentation: Visualizing the MHC Class I Peptide-Loading Bottleneck
.png){kind=icon}
OA
AI
DOI：10.1016/j.cub.2017.11.059.png)
.png){kind=icon}
.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
The peptide-loading complex is a bottleneck in antigen presentation by major histocompatibility complex (MHC) class I molecules. While the structures of its individual components were known, the recent report of the 7.2 angstrom structure of the entire complex now fits them into their functional context, explaining this monumental step in antigen acquisition by MHC class I molecules.
Keywords:
MOLECULES
COMPLEX
TAP
DEGRADATION
INHIBITOR
SELECTION
AI Summary
Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.