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Antigen uptake: Breaking convention
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DOI：10.1016/j.it.2026.06.008.png)
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Abstract
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More than 4 decades after the discovery of MHC restriction, it is clear that the phagocytosis of dying cells is not the only route by which macrophages acquire antigens. Fan and colleagues further expand this paradigm by showing that macrophages can sample a living cell’s cytosol and bypass classical endolysosomal processing.
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