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Antigenic Variation and Immune Recognition Inference From the COVID-19 Pandemic: An In Silico Comparative Analysis of Spike T Cell Epitopes From the SARS-CoV-2 Variants of Concern
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DOI：10.1111/irv.70286.png)
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Abstract
En 中文
With increased transmission but reduced disease severity, the Omicron SARS-CoV-2 variants have contributed to the multifaceted transition of COVID-19 from a global pandemic to an endemic disease. Nonetheless, the persistence of hypermutable viral variants and their ability to infect both vaccinated and previously infected individuals raise concerns about continued viral evolution and immune evasion.
Keywords:
antigenic variation
computational biology
immune recognition
SARS-CoV-2
T cell epitope
variants of concern
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