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Application of FTIR Spectroscopy for Identification of Blood and Leukemia Biomarkers: A Review over the Past 15 Years

delete2011-07-01
delete46
PRE
AI
L
Leila B. Mostaço-Guidolin *
L
Luciano Bachmann
DOI:10.1080/05704928.2011.565534delete
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Abstract

Abstract

En 中文
Fourier transform infrared (FTIR) spectroscopy is an effective and nondestructive method for monitoring cellular alterations. Combining the advantages of FTIR spectroscopy with the challenge of cellular characterization, the main objective of this review is to collect information related to the spectroscopic identification of blood cells, focusing on specific biochemical features of leukemia cells detected through FTIR spectral analysis. Some interesting results obtained by different authors regarding human promyelocytic leukemia, white blood cells, chronic lymphocytic leukemia, and human peripheral blood mononuclear cells are presented. In addition, the characterization of two types of cells, namely, leukemia T and a healthy human blood cells, is reported and the identification of biochemical markers provides important information that, associated with clinical examination, can assist in the diagnosis of diseases.
Keywords:
FTIR
leukemia
blood
cell
cancer

Journal

A
Applied Spectroscopy Reviews
IF:
5.4
Papers:
779
Citations:
3.7K

Organization

U
universidade de sao paulo
Scholars:
10.4W
Papers: 6.6W
Citations: 93