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Ascites-derived lipid barrier at the T cell synapse
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DOI:10.1038/s42255-026-01564-2.png)
Abstract
En 中文
Ovarian cancer ascites can blunt T cell attack, but the earliest steps affected have remained unclear. In this issue of Nature Metabolism, Brown et al. show that ascites-derived lipids disrupt T cell receptor organization and early activation, revealing a synaptic barrier to immunity.
Journal
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20.8
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1.6K
Citations:
1.4W
