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Association of Iron and Myelin Alterations in the Contralesional Dentate Nucleus and Thalamus With Functional Outcome in Acute Ischemic Stroke: A Susceptibility Source Separation Study

delete2026-07-02
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PRE
AI
H
Haorui Wan
Y
Yan Fu
S
Shun Zhang
G
Guiling Zhang
W
Wenzhen Zhu *
Y
Yi Wang *
DOI：10.1002/jmri.70431delete
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Abstract

Abstract

En 中文
Susceptibility alterations in deep gray matter (DGM) nuclei after acute ischemic stroke (AIS) may relate to impaired functional independence. However, conventional quantitative susceptibility mapping (QSM) cannot separate paramagnetic iron-related from diamagnetic myelin-related sources, potentially obscuring relevant pathophysiological alterations.
Keywords:
χ-separation
deep gray matter nuclei
iron
ischemic stroke
myelin
prognosis

Journal

Journal of Magnetic Resonance Imaging cover
Journal of Magnetic Resonance Imaging
IF:
3.5
Papers:
9.9K
Citations:
2.0W

Organization

W
weill cornell medicine
Scholars:
1.8K
Papers: 839
Citations: 0
H
huazhong university of science and technology
Scholars:
2.3W
Papers: 7.2K
Citations: 5
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