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Association of kynurenine metabolites with cognitive and psychological symptoms in post COVID-19 condition: A case-control study

delete2026-06-27
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L
Lynn Matits *
J
Jana Schellenberg
C
Claudia Schilling
D
Dietrich Rothenbacher
R
Raphael S. Peter
W
Winfried V. Kern
A
Alexandra Nieters
J
Jürgen M. Steinacker
D
Daniel A. Bizjak
DOI:10.1016/j.jpsychores.2026.112911delete
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Abstract

Abstract

En 中文
• PCC showed poorer cognitive function and higher psychological distress than controls. • Kynurenic acid/kynurenine showed opposite associations with cognitive function across groups. • Quinolinic acid/kynurenine was linked to psychological distress in PCC. • No robust associations between further metabolites and neuropsychological outcomes.
Keywords:
Kynurenine
Kynurenic acid/kynurenine
Quinolinic acid/kynurenine
Depressive symptoms
Anxiety
SARS-CoV-2
Cognitive function
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Journal

Journal of Psychosomatic Research cover
Journal of Psychosomatic Research
IF:
3.3
Papers:
8.7K
Citations:
1.6W

Organization

U
Ulm University
Scholars:
1.4K
Papers: 524
Citations: 0
H
heidelberg university
Scholars:
765
Papers: 251
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A
albert-ludwigs-university
Scholars:
10
Papers: 5
Citations: 0
U
ulm university hospital
Scholars:
66
Papers: 18
Citations: 0
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