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Associationof Static and Dynamic Pupillary Abnormalities with Retinal Microvasculopathy and Neurodegeneration in Diabetics
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DOI：10.1016/j.pdpdt.2026.105566.png)
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Abstract
En 中文
• Dynamic pupillometry can objectively and quantitatively evaluate diabetic autonomic neuropathy. • Both optical coherence tomography and optical coherence tomography angiography angiography are noninvasive techniques detecting subtle microvascular and neurodegenerative changes of retina. • Static pupillary abnormalities appear before clinical diabetic retinopathy, while dynamic reductions coincide with its onset. • Pupillary abnormalities correlate with retinal neural layer thinning and reduced vascular density in diabetics. • Evaluation for autonomic nervous dysfunction is recommended for all patients with diabetic retinopathy.
Keywords:
Pupil
Optical coherence tomography angiography
Retinal neurodegeneration
Diabetic retinopathy
Diabetic autonomic neuropathy
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