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Automatic Design of Microfluidic Gradient Generators
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AI
DOI：10.1109/ACCESS.2022.3158327.png)
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Abstract
En 中文
Concentration gradient generators are common components of microfluidic devices when specified mixing ratios have to be acquired. However, depending on their complexity, the creation of a suitable design is an elaborate task. Although approaches exist that derive such a design, they suffer from low flexibility and usability, which is why most concentration gradient generators are still mainly designed manually thus far-a time-consuming and error-prone task. To tackle this problem, we propose a method for the automatic design of tree-shaped concentration gradient generators and introduce a publicly available online tool that automatically generates a suitable design by adjusting the hydrodynamic resistances within the network. Moreover, the proposed tool is not only able to generate designs complying with user-defined requirements, such as mixing ratios, flow rates, and channel widths but also works for any number of outlets. Simulations using a Computational Fluid Dynamics (CFD) tool as well as evaluations on fabricated designs confirm the quality of the results obtained by the proposed tool.
Keywords:
Generators
Task analysis
Computational fluid dynamics
Databases
Liquids
Usability
Licenses
Concentration gradient generator
microfluidic mixer
design automation
Journal
IF:
3.6
Papers:
9.8W
Citations:
29.4W