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Balancing cell behavior at boundaries
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DOI：10.1083/jcb.201501107.png)
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Abstract
En 中文
The restriction of cell intermingling across boundaries is essential for the establishment of discrete tissues. Eph receptor signaling prevents intermingling at many boundaries. In this issue, Luu et al. (2015. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201409026) report a parallel pathway, mediated by Wnt signaling, Snail1, and paraxial protocadherin (PAPC). This pathway establishes a distinctive organization of cell adhesion and intercellular gaps at the interface between tissues.
Keywords:
TISSUE SEPARATION
XENOPUS GASTRULATION
MAINTENANCE
ADHESION
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