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Baseline Neuroinflammation Stratifies TSPO-PET Response to Disease-Modifying Therapy in Multiple Sclerosis

delete2026-07-01
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OA
AI
M
Marlene T. Morch
M
Markus Matilainen
G
Giulia N. Baldrighi
M
Marjo Nylund
M
Maija Saraste
L
Laura Airas *
DOI:10.1002/acn3.70472delete
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Abstract

Abstract

En 中文
To investigate which baseline clinical and imaging characteristics best predict TSPO-PET-measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker-based clinical trials targeting glial activation.
Keywords:
DMT
microglial activation
multiple sclerosis
predictive biomarker
TSPO-PET
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Journal

Annals of Clinical and Translational Neurology cover
Annals of Clinical and Translational Neurology
IF:
3.9
Papers:
2.6K
Citations:
7.4K

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U
university of turku
Scholars:
2.0K
Papers: 893
Citations: 0
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