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Bayesian approach to decompression sickness model parameter estimation

delete2017-03-01
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PRE
AI
L
Laurens E. Howle *
P
P Weber
J
Jonathan M. Nichols
DOI:10.1016/j.compbiomed.2017.01.006delete
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Abstract

Abstract

En 中文
We examine both maximum likelihood and Bayesian approaches for estimating probabilistic decompression sickness model parameters. Maximum likelihood estimation treats parameters as fixed values and determines the best estimate through repeated trials, whereas the Bayesian approach treats parameters as random variables and determines the parameter probability distributions. We would ultimately like to know the probability that a parameter lies in a certain range rather than simply make statements about the repeatability of our estimator. Although both represent powerful methods of inference, for models with complex or multi-peaked likelihoods, maximum likelihood parameter estimates can prove more difficult to interpret than the estimates of the parameter distributions provided by the Bayesian approach. For models of decompression sickness, we show that while these two estimation methods are complementary, the credible intervals generated by the Bayesian approach are more naturally suited to quantifying uncertainty in the model parameters.
Keywords:
Bayesian
Markov-Chain-Monte-Carlo
Decompression sickness
Decompression model
Decompression illness

Journal

Computers in Biology and Medicine cover
Computers in Biology and Medicine
IF:
6.3
Papers:
8.4K
Citations:
3.3W

Organization

D
Duke University
Scholars:
6.3W
Papers: 5.7W
Citations: 6.5W
United States Navy cover
United States Navy
Scholars:
6.7K
Papers: 5.5K
Citations: 175
Cited Papers

Cited Papers

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Marginal DCS events: their relation to decompression and use in DCS models
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PREAI
errHowle, Laurens E.; Weber, Paul W.; Vann, Richard D.; Campbell, Mark C.
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