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Best practice for CRISPR design using current tools and resources
DOI:10.1016/j.ymeth.2019.05.019.png)
Abstract
En 中文
Users facing the task of designing gRNAs for a CRISPR-mutagenesis experiment are typically confronted with a large variety of possible tools and existing libraries. Here we examine the design principles for such resources, and suggest a best practice which allows a user to evaluate and effectively use any of the existing CRISPR design tools or genome-wide libraries.
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