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Beyond senescence entry: individual-cell fates, population outcomes and therapeutic implications in ageing and disease
G
Y
J
DOI:10.1016/j.arr.2026.103293.png)
Abstract
En 中文
• Separates individual-cell fates from population persistence and resolution. • Defines strict escape as sustained proliferation after validated senescence. • Integrates cell-intrinsic and tissue-level mechanisms governing senescent-cell fate. • Sets evidence standards for fate assignment and matches senotherapies to outcomes.
Journal
IF:
12.4
Papers:
3.5K
Citations:
2.3W
Organization
No organization information available
