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Bidirectional functional genomics using CRISPR-KOALA

delete2026-07-31
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PRE
AI
K
Khalid N. Al‐Zahrani *
DOI：10.1038/s41576-026-00997-5delete
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Abstract

Abstract

En 中文
In this Tools of the Trade article, Khalid Al-Zahrani introduces CRISPR-KOALA, a new CRISPR-based platform that enables simultaneous loss- and gain-of-function screening in vivo, helping to pinpoint cancer driver genes hidden within large chromosome-scale copy number alterations.

Journal

Nature Reviews Genetics cover
Nature Reviews Genetics
IF:
52
Papers:
4.0K
Citations:
4.3W

Organization

U
university of toronto
Scholars:
14.5W
Papers: 11.9W
Citations: 165