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Bimetallic Anilinopyridinate ruthenium(II,III) complexes: Synthesis, characterisation, and in vitro selective cytotoxicity towards MCF-7 breast cancer cells
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DOI：10.1016/j.jinorgbio.2026.113399.png)
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Abstract
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• Five new mono-substituted anilinopyridinate diruthenium(II,III) complexes were successfully synthesised and characterised. • Crystal structures of the complexes C1, C3, and C5 reveal a lantern-type geometry. • substition at the para position of the anilinopyridinate ligands influences the lability of the axial chloride ligand. • Complex C3 shows high potency and selectivity against ER+ve MCF-7 breast cancer cells. • Complex C3 effectively inhibits the long-term survival and proliferation of MCF-7 human breast cancer cells.
Keywords:
Lantern-type
Diruthenium(II,III)
Breast cancer
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