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Biodegradable tetrasulfide bonds incorporated mesoporous polyamidoamine nanoplatform for enhancing antitumor efficiency via photothermal enhanced GSH depletion
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DOI：10.1016/j.matdes.2025.115406.png)
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Abstract
En 中文
• Mesoporous polydopamine doped with tetrasulfide bonds were fabricated for the first time. • It has satisfactory photothermal conversion efficiency and effective intracellular GSH consumption. • Potent PTT and ROS generation were achieved for in vitro and in vivo tumor cell killing.
Keywords:
Tetrasulfide bonds
GSH exhausting
PTT
Tumor targeting
Synergistic tumor suppression
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