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Bioinspired engineering of simplified type I photosensitizers against hypoxic oral squamous cell carcinoma
J
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李
K
DOI:10.1016/j.gce.2026.04.002.png)
Abstract
En 中文
• Novel photosensitizers based on purine skeletons simplify photosensitizer fabrication remarkably • PCP exhibits potent Type I ROS generation. • PCP-mediated photodynamic therapy effectively ablated OSCC tumor tissue and inhibited tumor growth.
Keywords:
Photodynamic therapy (PDT)
Oral squamous cell carcinoma
mitochondrial disorder
Type I ROS
Purine derivatives
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