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Bioinspired engineering of simplified type I photosensitizers against hypoxic oral squamous cell carcinoma

delete2026-04-07
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OA
AI
J
Jiayao Zhang
M
Mingzhe Bao
X
Xiao‐Yun Ran
L
Lei Shi *
Z
Zhiyong Guo *
X
Xiao‐Qi Yu
李昆 (Kun Li) *
K
Kangkang Yu *
DOI:10.1016/j.gce.2026.04.002delete
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Abstract

Abstract

En 中文
• Novel photosensitizers based on purine skeletons simplify photosensitizer fabrication remarkably • PCP exhibits potent Type I ROS generation. • PCP-mediated photodynamic therapy effectively ablated OSCC tumor tissue and inhibited tumor growth.
Keywords:
Photodynamic therapy (PDT)
Oral squamous cell carcinoma
mitochondrial disorder
Type I ROS
Purine derivatives
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Green Chemical Engineering cover
Green Chemical Engineering
IF:
7.6
Papers:
350
Citations:
1.5K

Organization

X
Xihua University
Scholars:
6.2K
Papers: 3.6K
Citations: 4.1K
S
Sichuan University
Scholars:
1.4W
Papers: 4.3K
Citations: 12.9W
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