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Biological variation of serum Anti-Müllerian Hormone in healthy adult men
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DOI：10.1016/j.cca.2026.121068.png)
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Abstract
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Biological variation of serum AMH was investigated for the first time in healthy adult men. • Twenty-one participants were monitored over four weeks, yielding 84 serum samples. • Within-subject biological variation (CVI) was 3.5% (95% CI: 2.93–4.30), and between-subject biological variation (CVG) was 34.72% (95% CI: 26.38–50.75). • The individuality index was 0.1, indicating high individuality and limited utility of population-based reference intervals. • Asymmetric RCV thresholds (+9%/−8.2%) and desirable APSs were established, supporting RCV and personalized reference intervals in clinical monitoring.
Keywords:
serum AMH
biological variation
healthy adult men
individuality index
reference intervals
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